United States securities and exchange commission logo March 11, 2022 Charles Fernandez Chief Executive Officer NextPlat Corp 18851 N.E. 29th Ave., Suite 700 Aventura, FL 33180 Re: NextPlat Corp Registration Statement on Form S-3 Filed February 15, 2022 File No. 333-262748 Dear Mr. Fernandez: We have limited our review of your registration statement to those issues we have addressed in our comments. In some of our comments, we may ask you to provide us with information so we may better understand your disclosure. Please respond to this letter by amending your registration statement and providing the requested information. If you do not believe our comments apply to your facts and circumstances or do not believe an amendment is appropriate, please tell us why in your response. After reviewing any amendment to your registration statement and the information you provide in response to these comments, we may have additional comments. Registration Statement on Form S-3 Prospectus Summary Our Company, page 3 1. You state that your "new platform will enable the use of a range of digital assets including non-fungible tokens ("NFTs") in e-commerce and in community-building activities." Please disclose the status of the development of this platform, what type of digital assets it will allow, and the expected role of such digital assets. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Charles Fernandez NextPlat Corp March 11, 2022 Page 2 Refer to Rules 460 and 461 regarding requests for acceleration. Please allow adequate time for us to review any amendment prior to the requested effective date of the registration statement. Please contact Priscilla Dao, Staff Attorney, at (202) 551-5997 or Jan Woo, Legal Branch Chief, at (202) 551-3453 with any questions. Sincerely, FirstName LastNameCharles Fernandez Division of Corporation Finance Comapany NameNextPlat Corp Office of Technology March 11, 2022 Page 2 cc: Johnathan C. Duncan FirstName LastName