United States securities and exchange commission logo November 28, 2022 Charles Fernandez Chief Executive Officer NextPlat Corp. 3250 Mary St., Suite 410 Coconut Grove, FL 33133 Re: NextPlat Corp. Registration Statement on Form S-3 Filed November 21, 2022 File No. 333-268488 Dear Charles Fernandez: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Lauren Pierce, Staff Attorney, at (202) 551-3887 or Joshua Shainess, Legal Branch Chief, at (202) 551-7951 with any questions. Sincerely, Division of Corporation Finance Office of Technology cc: Marc Rivera